Recombinant production of mixtures of antibodies
CA 2872136 C · Owner: Merus B.V. · Inventors: Brus, Ronald Hendrik Peter; Logtenberg, Ton; Bout, Abraham
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides methods for producing mixtures of antibodies from a single host cell clone. Thereto a nucleic acid sequence encoding a light chain and nucleic acid sequences encoding different heavy chains are expressed in a recombinant host cell. The antibodies in the mixtures according to the invention suitably comprise identical light chains paired to different heavy chains capable of pairing to the light chain thereby forming functional antigen binding domains. Mixtures of antibodies are also provided by the invention. Such mixtures can be used in a variety of fields.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 15, 2003 and granted June 20, 2017. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 15, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 15, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.