Polysaccharide-protein conjugate vaccines
CA 2844154 C · Owner: The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services · Inventors: Lee, Che-Hung Robert; Frasch, Carl E.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods for synthesis and manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency such that a simplified purification process can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 6, 2004 and granted December 20, 2016. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 6, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 6, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.