Genetically-engineered non-toxic bleb vaccine
CA 2820314 C · Owner: Smithkline Beecham Biologicals S.A. · Inventors: Thonnard, Joelle; Dequesne, Guy; Berthet, Francois-Xavier Jacques
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to an immuno-protective and non-toxic Gram- negative bleb vaccine suitable for paediatric use. Examples of the Gram-negative strains from which the blebs are made are N. meningitidis M. catarrhalis and H. influenzae. The blebs of the invention are improved by one or more genetic changes to the chromosome of the bacterium including up-regulation of protective antigens down-regulation of immunodominant non-protective antigens and detoxification of the Lipid A moiety of LPS.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 31, 2000 and granted April 26, 2016. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 31, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 31, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.