Hematopoietic stem cells treated by in vitro fucosylation and methods of use
CA 2816907 C · Owner: Xia, Lijun · Inventors: Xia, Lijun; Mcever, Rodger P.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method of in vitro fucosylation of selectin ligands on cord blood-derived hematopoietic stem cells for bone marrow transplantation is disclosed. In this method an effective amount of an .alpha.1,3-fucosyltransferase e.g. .alpha.1,3-fucosyltransferase VI, is used in vitro to treat cord blood-derived hematopoietic stem cells to convert non-functional PSGL-1 or other ligands on the cell surface into functional forms that bind selectins especially P-selectin or E- selectin. The treated cells have enhanced effectiveness in reconstituting bone marrow in patients in need of such therapy.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 3, 2004 and granted July 5, 2016. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 3, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 3, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.