Multi-arm polymer prodrugs
CA 2799282 C · Owner: Nektar Therapeutics · Inventors: Zhao, Xuan; Ren, Zhongxu; Bentley, Michael D.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Provided herein are water-soluble prodrugs. The prodrugs of the invention comprise a water-soluble polymer having three or more arms at least three of which are covalently attached to an active agent e.g. a small molecule. The conjugates of the invention provided an optimal balance of polymer size and structure for achieving improved drug loading since the conjugates of the invention possess three or more active agents releasably attached to a multi- armed water soluble polymer. The prodrugs of the invention are therapeutically effective and exhibit improved properties in-vivo when compared to unmodified parent drug.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 17, 2004 and granted May 17, 2016. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 17, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 17, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.