Uncoupled productive and catabolic host cell pathways
CA 2794446 C · Owner: Genencor International, Inc. · Inventors: Dodge, Timothy; Valle, Fernando
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides methods for producing products comprising improved host cells genetically engineered to have uncoupled productive and catabolic pathways. In particular the present invention provides host cells having a modification in nucleic acid encoding an endogenous enzymatic activity that phosphorylates D--glucose at its 6th carbon and/or a modification of nucleic acid encoding an enzymatic activity that phosphorylates D-gluconate at its 6th carbon. Such improved host cells are used for the production of products such as, ascorbic acid intermediates. Methods for making and using the improved host cells are provided. Nucleic acid and amino acid sequences for glucokinase and …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 4, 2002 and granted September 8, 2015. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 4, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 4, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.