T1r taste receptors and genes encoding same

Abstract From the Canadian patent

Newly identified mammalian taste-cell-specific G protein-coupled receptors and the genes and cDNA encoding said receptors are described. Specifically T1R G protein- coupled receptors active in taste-signaling and the genes and cDNA encoding the same are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular taste stimulus in a mammal are also described as are methods for generating novel molecules or combinations or molecules that elicit a predetermined taste perception in a mammal and methods for stimulating one or more tastes. Further methods for stimulating or blocking taste …