Methods for producing enantiomerically pure .alpha.-substituted carboxylic acids
CA 2718302 C · Owner: Verenium Corporation · Inventors: Madden, Mark (Deceased); Robertson, Dan; Weiner, David Paul
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
In accordance with the present invention there are provided methods for producing enantiomerically pure a-substituted carboxylic acids such as, for example, .alpha.-amino acids and .alpha.-hydroxy acids said method comprising combining an aldehyde or ketone with a cyanide and ammonia or an ammonium salt or an amine in the presence of a nitrilase or a polypeptide having nitrilase activity which stereoselectively hydrolyzes the amino nitrite or cynohydrin intermediate under conditions sufficient to produce the carboxylic acid.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 29, 2000 and granted December 4, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended December 29, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 29, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.