Method of using tetracycline compounds for inhibition of nitric oxide production
CA 2670296 A1 · Owner: The Research Foundation Of State University Of New York · Inventors: Greenwald, Robert A.; Trachtman, Howard; Ramamurthy, Nungavaram S.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention is a method of inhibiting the production of nitric oxide (NO) in an in vivo, in vitro, or ex vivo biological system. The method employs a tetracycline compound to inhibit the production of NO and/or to inhibit the expression or activity of an inducible isoform ot nitric oxide synthase (iNOS). , Preferably, the tetraclycine compound has inhibitory activity for metalloproteinases. Also it is preferred that the tetracycline compound is provided to the biological system in an amount which has little or no antibacterial , activity in the system. Accordingly preferred tetraclycine compounds are , tetracycline compounds which have been modified to reduce or eliminate their …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 21, 1997. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 21, 2017.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 21, 2019.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.