Antibody fragment-polymer conjugates and humanized anti-il-8 monoclonal antibodies
CA 2615918 C · Owner: Presta, Leonard G. · Inventors: Shahrokh, Zahra; Leong, Steven R.; Koumenis, Iphigenia
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous polymer wherein the apparent size of the conjugate is at least about 500 kD. The conjugate exhibits substantially improved half-life mean residence time, and/or clearance rate in circulation as compared to the underivatized parental antibody fragment.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 20, 1998 and granted November 26, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended February 20, 2018.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 20, 2020.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.