Methods of production of modified proteins
CA 2594178 C · Owner: Hodges, Robert A. · Inventors: Xu, Ming-Qun; Noren, Christopher J.; Chong, Shaorong S.C.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention is directed to modified proteins and methods of their production. The modified proteins comprise a controllable intervening protein sequence (CIVPS) inserted into a target protein the CIVPS being capable of excision from or cleavage of the modified protein under predetermined conditions in cis or in trans i.e. increase in temperature, exposure to light unblocking of amino acid residues by dephosphorylation treatment with chemical reagents or deglycosylation. If desired the modified protein can be subjected to these conditions. The CIVPS may also be inserted into a region that substantially inactivates target protein activity.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 19, 1996 and granted August 21, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended June 19, 2016.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 19, 2018.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.