Prevention of incorporation of non-standard amino acids into protein
CA 2539996 C · Owner: O'Neil, Julia P. · Inventors: Bogosian, Gregg; O'Neil, Julia P.; Smith, Hong Q.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The instant invention is drawn to the methods and compositions necessary to provide recombinant proteins with a substantially reduced or eliminated content of norleucine or other non-standard amino acids. Various embodiments of the invention provide for the substantial elimination of the incorporation of non-standard amino acids into recombinant proteins by the co-expression or enhanced expression of a protein (or the enzymatically active portion thereof) capable of degrading norleucine or other non-standard amino acids including , norvaline, beta-methylnorleucine and homoisoleucine. In certain particular embodiments of the invention, the norleucine is degraded by a glutamate …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 23, 2004 and granted November 26, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 23, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 23, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.