Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation
CA 2538697 C · Owner: Teva Sante · Inventors: Prat, Laurence; Duret, Gerard; Rebiere, Francois
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a method for preparing a sulphoxide compound of formula (I) either as a single enantiomer or in an enantiomerically enriched form, comprising the steps of : a) contacting a pro-chiral sulphide of formula (II) with a metal chiral complex, a base and an oxidizing agent in an organic solvent ; and optionally b) isolating the obtained sulphoxide of formula (I) wherein n, Y, R1, R1a, R2 and R2a are as defined in claim 1.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 17, 2004 and granted November 13, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 17, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 17, 2026.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.