Malonamide derivatives blocking the activity of gama-secretase
CA 2537440 C · Owner: Galley, Guido · Inventors: Wostl, Wolfgang; Flohr, Alexander; Galley, Guido
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to malonamide derivatives of formula (I) wherein: R1 is , one of the following groups (Formulae a) b), c), d)); R2 is lower alkyl, lower alkinyl -(CH2)n-O-lower alkyl, -(CH2)n-S-lower alkyl -(CH2)n-CN, -, (CR'R")n-CF3, -(CR'R")n-CHF2 -(CR'R")n-CH2F, -(CH2)n-C(O)O-lower alkyl -, (CH2)n-halogen, or is -(CH2)n-cycloalkyl optionally substituted by one or , more substituents selected from the group consisting of phenyl halogen or , CF3; R',R" are independently from n and from each other hydrogen lower alkyl, lower alkoxy, halogen or hydroxy; R3 R4 are independently from each other , hydrogen lower alkyl, lower alkoxy, phenyl or halogen; R5 is hydrogen lower , alkyl, …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed August 31, 2004 and granted July 10, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended August 31, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 31, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
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Sources & verification
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.