Process for the preparation of n-arylmorpholinones

Abstract From the Canadian patent

The invention relates to a method for production of a compound of formula (I), and precursors for the same wherein the compound of formula I , is: (see formula I), or a salt thereof, (see formula II) in which X denotes ,R1 denotes NO2, CN COOR3, CON(R3)2, COR3, SO2R4, SO2N(R3)2 CF3, F or Cl, R2 denotes H, Hal, A, OR3 N(R3)2, NO2, CN, COOR3, CON(R3)2, NR3COA NR3CON(R3)2, NR3COOR3, NR3SO2A, -C(R5)2n-Ar -C(R5)2n-Het, -C(R5)2n-cycloalkyl, COR3 SO2N(R3)2 , or , SO2R4, R3 denotes H, A -C(R5)2n-Ar or -C(R5)2n-Het, R4 denotes A -, C(R5)2n-Ar or , -C(R5)2n-Het, R5 denotes H or A' Ar denotes unsubstituted or mono-, di- or trisubstituted phenyl, Het denotes optionally substituted mono- or bicyclic …