Selection of allosteric regulators with class iii g protein-coupled receptors depleted of the extracellular domain
CA 2526695 C · Owner: Prezeau, Laurent · Inventors: Prezeau, Laurent; Gaven, Florence; Pin, Jean-Philippe
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a method for identifying and selecting a compound acting as an allosteric regulator of a GPCR-III. According to said method the activity level of a recombinant GPCR-III (GPCR-III-?) essentially depleted of the extracellular domain of the corresponding native GPCR-III in the presence of a given compound, is compared to the activity level of the same GPCR-III-? in the absence of said compound enabling positive or negative allosteric regulators of GPCRs-III to be identified and selected. The invention also relates to the application of one such method for identifying and selecting compounds of interest in fields of activity such as pharmacy the agro-food industry, the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 11, 2004 and granted July 16, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended May 11, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 11, 2026.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.