Process for the preparation of amorphous calcium salt of atorvastatin
CA 2520740 C · Owner: Lek Pharmaceuticals D.D. · Inventors: Copar, Anton; Sorsak, Gorazd; Antoncic, Ljubomir
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Present invention refers to the process of preparing amorphous atorvastatin calcium without intermediate isolation of crystal or undefined mixture of crystal and amorphous atorvastatin calcium respectively. Forming of calcium , atorvastatin salt is carried out in a mixture of chlorinated organic solvent or cyclic hydrocarbon solvent, respectively the non-hydroxylic organic , solvent, and water the source of calcium ions is calcium acetate or calcium chloride, respectively.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 9, 2004 and granted June 5, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 9, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 9, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.