Sinus delivery of sustained release therapeutics

Abstract From the Canadian patent

The invention provides biodegradable implants for treating sinusitis. The biodegradable implants have a size, shape density, viscosity, and/or , mucoadhesiveness that prevents them from being substantially cleared by the mucociliary lining of the sinuses during the intended treatment period. The biodegradable implants include a sustained release therapeutic e.g. an , antibiotic, a steroidal anti-inflammatory agent or both. The biodegradable , implants may take various forms such as rods, pellets, beads, strips, or microparticles, and may be delivered into a sinus in various pharmaceutically acceptable carriers.