Model for studying the role of genes in tumor resistance to chemotherapy
CA 2516022 C · Owner: Cold Spring Harbor Laboratory · Inventors: Lowe, Scott W.; Pelletier, Jerry; De Stanchina, Elisa
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides the components of in vivo and in vitro systems and methods which use them to study the effects of altered expression of a gene activity, such as the human akt, bcl-2 eIF4E or PTEN activities, on the , descendants of stem cells that have been engineered to give rise to hematopoietic tumorigenic or tumor cells such as lymphomas, with a high , frequency. The present invention provides vectors cells and mammals, and , methods which in part depend on such products useful for understanding , tumorigenesis and its treatments and in particular, for identifying and studying inhibitors and activators associated with tumor cell growth and growth inhibition, cell death …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 17, 2004 and granted May 29, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended February 17, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 17, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.