Pharmaceutical co-crystal compositions of drugs such as carbamazeptine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen

Abstract From the Canadian patent

A pharmaceutical composition comprising a co-crystal of an API and a cocrystal forming compound; wherein the API has at least one functional group selected from ether, thioether, alcohol thiol, aldehyde, ketone, thioketone, nitrate ester phosphate ester, thiophosphate ester, ester thioester, sulfate , ester, carboxylic acid phosphonic acid, phosphinic acid, sulfonic acid amide, primary amine, secondary amine, ammonia tertiary amine, sp2 amine, thiocyanate cyanamide, oxime, nitrile diazo, organohalide nitro, s-, heterocyclic ring, thiophene n-heterocyclic ring, pyrrole, oheterocyclic ring, furan, epoxide, peroxide, hydroxamic acid imidazole, pyridine and the , co-crystal forming compound …