Terminal-phosphate-labeled nucleotides and methods of use
CA 2513672 C · Owner: Fuller, Carl · Inventors: Fuller, Carl; Kumar, Shiv; Nelson, John
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to improved methods of detecting a target using a labeled substrate or substrate analog. The methods comprise reacting the substrate or substrate analog in an enzyme-catalyzed reaction which produces a labeled moiety with independently detectable signal only when such substrate or substrate analog reacts. The present invention in particular, describes , methods of detecting a nucleic acid in a sample based on the use of terminal-, phosphate-labeled nucleotides as substrate for nucleic acid polymerases. The methods provided by this invention utilize a nucleoside polyphosphate dideoxynucleoside polyphosphate, or deoxynucleoside polyphosphate analogue which …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 30, 2004 and granted January 14, 2014. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 30, 2024.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 30, 2026.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.