Chimeric protein for the screening of agonists and antagonists of cell signalling pathways that are dependent on g-protein-coupled receptors
CA 2511213 A1 · Owner: Grunwald, Didier · Inventors: Dupuis, Alain; Grunwald, Didier; De Waard, Michel
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to a chimeric protein which is derived from a high-threshold calcium channel and which is characterised in that it consists of at least one .beta. subunit or a fragment of same comprising at least the BID domain which is fused at the NH¿2? or COOH end thereof with the I-II loop of an .alpha.¿1? subunit or a fragment of same comprising at least the AID domain. The invention also relates to the applications of said protein in the study of cell signalling pathways that are dependent on G-protein-coupled receptors (GPCR) and the identification of compounds that modulate the activity of G proteins. ?¿
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 22, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 22, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 22, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.