Process for the preparation of phosphitylation agents
CA 2510473 C · Owner: Dinizo, Stephan Edward · Inventors: Dinizo, Stephan Edward; Hardy, Jonathan Mark
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for the preparation of a compound of formula R1-Y1-P(NR2R3 )2 is provided. The process comprises reacting a compound of formula PX3 with a compound of formula HNR2R3 to form a compound of formula X-P(NR2R3)2; and reacting the compound of formula X-P(NR2R3)2 with a compound of formula R1-Y1- H in the presence of a hydrocarbon solvent to form the compound of formula R1- Y1-P(NR2R3 )2. R1 represents a phosphorus protecting group; R2 and R3 each independently represent an alkyl, preferably a C1-6alkyl group, or R2 and R3 , are joined, together with the N to which they are attached to form a 5-7 , membered ring; Y1 represents O or S preferably O; and X represents a halogen …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 16, 2003 and granted February 21, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended December 16, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 16, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.