A method for improving protein production
CA 2510179 C · Owner: Van Blokland, Henricus Johannes Maria · Inventors: Van Blokland, Henricus Johannes Maria; Otte, Arie Pieter
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to the fields of biochemistry molecular biology, and , pharmacology. More specifically the present invention relates to the production of proteins in a (host) cell. The present invention uses a TRAnscription Pause (TRAP) sequence to enhance a protein expression characteristic of a protein expression unit. The TRAP sequence is thought to at least in part prevent formation of antisense RNA or to at least in part prevent transcription to enter said protein expression unit. In one embodiment, the invention provides a method for expression of at least one protein of interest in a cell comprising providing said cell with at least one protein expression unit which …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 2, 2003 and granted April 23, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended December 2, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 2, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.