Bacterial cell component-unresponsive model mouse
CA 2509345 C · Owner: Akira, Shizuo · Inventors: Takeda, Kiyoshi; Takeuchi, Osamu; Akira, Shizuo
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A knockout mouse which is unresponsive to peptidoglycan a lipoprotein/lipopeptide and the like and is useful for elucidating the contribution of individual members of the TLR family to a signaling stimulated with bacterial cell components in vivo in particular, the role of TLR2 and MyD88 in vivo. A bacterial cell component-unresponsive knockout mouse is generated by a process comprising the steps of: a targeting vector is constructed by replacing a whole or a part of a gene fragment of an exon region containing a cytoplasmic region of TLR2 or MyD88 gene and the like with a plasmid having a poly A signal and a marker gene; the targeting vector is introduced into an embryonic stem cell; the …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 13, 2000 and granted March 12, 2013. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 13, 2020.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 13, 2022.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.