3-(2-hydroxy-phenyl)-1h-pyrazole-4-carboxylic acid amide derivatives as hsp90 inhibitors for the treatment of cancer
CA 2508574 A1 · Owner: Cancer Research Technology Ltd · Inventors: Dymock, Brian William; Drysdale, Martin James; Brough, Paul Andrew
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Compounds of formula (IA) or (IB) or salts N-oxides, hydrates or solvates , thereof are Inhibitors of HSP90 and useful in the treatment of, for example cancer: formula (IA), formula (IB) wherein Ar is an aryl or heteroaryl radical which is linked via a ring carbon, and which is substituted by a hydroxy group on a carbon in the 2-position, and which is otherwise either unsubstituted or optionally substituted; R1 is hydrogen or optionally substituted C1-C6 alkyl; R2 is hydrogen, optionally substituted cycloalkyl cycloalkenyl, C1-C6 alkyl, C1-C6alkenyl or C1-C6 alkynyl; or a carboxyl, carboxamide or carboxyl ester group; and R3 is a carboxamide group.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed December 4, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended December 4, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by December 4, 2025.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.