Process for the racemisation of enantiomerically enriched alpha-amino nitriles
CA 2506892 A1 · Owner: Broxterman, Quirinus Bernardus · Inventors: Kaptein, Bernardus; Verzijl, Gerardus Karel Maria; Broxterman, Quirinus Bernardus
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Process for the racemisation of an enantiomerically enriched .alpha.-amino nitrile characterized in that the enantiomerically enriched .alpha.-amino nitrile is contacted with a lewis acid catalyst. Preferably an aprotic solvent is used. The lewis acid catalyst preferably comprises a metal chosen from main group elements IA-IVA of the Periodic Table (CAS version) the transition , metals and the lanthanides in particular Al, Ti, Zr, or lanthanides. The catalsyt for example has the general structure MnXpSqLr and preferably is , chosen from the group of aluminum alkoxides aluminum alkyls, lanthanide , alkoxydes and lanthanocenes. The racemisation may be performed in combination with a …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 3, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 3, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 3, 2025.
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