Methods for the identification of agents that modulate the structure and processing of beta-amyloid precursor protein
CA 2504870 A1 · Owner: Icogenex Corporation · Inventors: Hagen, Frederick S.; Lannfelt, Lars; Gellerfors, Par
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides methods for the screening and identification of agents from a large library of molecular structures that can alter the cleavage of amyloid precursor protein (AP). Agents identified by the methods of the present invention that modify the cleavage of APP can be used in the treatment and prevention of Alzheimer's disease. The methods select for and identify effector agents that bind to APP causing a structural change in the structure of APP in such a way that the efficiency of the cleavage of a secretase is modulated. Further, the methods are carried out in an in vivo system that provides for physiological conditions similar or identical to conditions …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed November 4, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended November 4, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by November 4, 2025.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.