Substrates for o6-alkylguanine-dna alkyltransferase
CA 2501063 A1 · Owner: Ecole Polytechnique Federale De Lausanne (Epfl) · Inventors: Bieri, Christoph; Kindermann, Maik; Johnsson, Kai
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention relates to methods of transferring a label from novel substrates to O6-alkylguanine-DNA alkyltransferases (AGT) and O6-alkylguanine- DNA alkyltransferase fusion proteins, and to novel substrates suitable in such methods. Proteins of interest are incorporated into an AGT fusion protein the , AGT fusion protein is contacted with particular AGT substrates carrying a label, and the AGT fusion protein is detected and optionally further manipulated using the label in a system designed for recognising and/or handling the label. The particular AGT substrates used in the method of the invention are O6-substituted guanine derivatives or related nitrogen containing …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed October 1, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended October 1, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by October 1, 2025.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.