Medical device having hydration inhibitor

Abstract From the Canadian patent

Medical devices , comprising an interventional component for delivering multiple beneficial , agents in which a hydration inhibitor controls release of at least one beneficial agent from the device. The hydration , inhibitor is relatively less hydrophilic than the beneficial agent and preferably is a drug. Suitable beneficial agents include (I) dexamethasone, estradiol, anti-proliferative agents anti-platelet , agents, anti-inflammatory agents anti-thrombotic agents, cytotoxic drugs. agents that inhibit cytokine or chemokine binding, cell de-differentiation , inhibitors anti-lipaedemic agents, matrix metalloproteinase inhibitors cytostatic drugs, or combinations , of these drugs …