Improved bacterial outer membrane vesicles
CA 2497165 C · Owner: Chiron Srl · Inventors: Pizza, Mariagrazia; Serruto, Davide; Rappuoli, Rino
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Existing methods of meningococcal OMV preparation involve the use of detergent during disruption of the bacterial membrane. According to the invention membrane disruption is performed substantially in the absence of detergent. The resulting OMVs which retain important bacterial immunogenic components particularly (i) the protective NspA surface protein (ü) protein NMB2132 and , (iii) protein NMB 1870.A Typical process involves the following steps: (a) treating bacterial cells in the substantial absence of detergent; (b) centrifuging the composition from step (a) to separate the outer membrane vesicles from treated cells and cell debris and collecting the supernatant; , (c) performing a …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 1, 2003 and granted October 20, 2015. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 1, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 1, 2025.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.