Methods and compositions for modulating xbp-1 activity
CA 2496897 C · Owner: President And Fellows Of Harvard College · Inventors: Iwakoshi, Neil; Glimcher, Laurie H.; Lee, Ann-Hwee
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention provides methods and compositions for modulating the expression processing, post-translational modification and/or activity of XBP-1 protein, or a protein in a signal transduction pathway involving XBP-1. Exemplary XBP-1 activities that can be modulated using the methods and compositions of the invention include: the Unfolded Protein Response (UPR) plasma cell , differentiation, immunoglobulin production apoptosis and the production of IL-, 6. The present invention also pertains to methods for identifying compounds that modulate the expression, processing post-translational modification, and/or activity of XBP-1 protein or a molecule in a signal transduction pathway …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed September 2, 2003 and granted January 31, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended September 2, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by September 2, 2025.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.