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Method for manufacturing crystalline form i of clopidogrel hydrogen sulphate

CA 2495823 A1 · Owner: Stepankova, Hana · Inventors: Veverkova, Eva; Stepankova, Hana; Vodny, Stefan

CIPO record

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Abstract From the Canadian patent

A method for manufacturing hydrogen sulphate (alpha S) of the alpha-(2chlorophenyl)-6,7~dihydro-thieno~3,2-c~pyridine-5(4H)-acetic acid methyl ester (clopidogrel hydrogen sulphate) of formula I in crystalline Form I, wherein , the compound of formula is separated out of a solution of clopidogrel in the form of the free base or salt in a solvent selected from the series of primary, secondary or tertiary C1-C5 alcohols their esters with Cl-C4 , carboxylic acids or optionally of mixtures thereof.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed August 26, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended August 26, 2023.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by August 26, 2025.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledAugust 26, 2003
GrantedNo grant recorded
Term endedAugust 26, 2023
Patent numberCA 2495823 A1
Classification (IPC)C07D495/04

Timeline

Timeline From CIPO dates

2004200620082010201220142016201820202022Application filedAug 26, 2003Term endedAug 26, 2023

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.