Biaryl diazabicycloalkane amides as nicotinic acetylcholine agonists

Abstract From the Canadian patent

Nicotinic acetylcholine receptor of formula (I) wherein D Ar1, E and Ar2 are , as defined in the specification enantiomers, pharmaceutically acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same in the treatment or prophylaxis of psychotic disorders intellectual impairment disorders, Alzheimer~s disease learning deficit, cognition deficit, attention deficit memory loss, Lewy Body Dementia, Attention Deficit Hyperactivity Disorder anxiety, schizophrenia, mania or , manic depression Parkinson~s disease, Huntington~s disease Tourette~s , syndrome, neurodegenerative disorders in which there is loss of cholinergic synapse, jetlag, cessation …