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Expired Canadian patentCanada

Compositions and methods for sirna inhibition of angiogenesis

CA 2493499 C · Owner: Tolentino, Michael J. · Inventors: Tolentino, Michael J.; Reich, Samuel Jotham

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Abstract From the Canadian patent

RNA interference using small interfering RNAs which are specific for the vascular endothelial growth factor (VEGF) gene and the VEGF receptor genes Flt~1 and Flk-l/KDR inhibit expression of these genes. Diseases which involve angiogenesis stimulated by overexpression of VEGF such as diabetic , retinopathy, age related macular degeneration and many types of cancer can be , treated by administering the small interfering RNAs.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed July 18, 2003 and granted April 12, 2016. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 18, 2023.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 18, 2025.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledJuly 18, 2003
GrantedApril 12, 2016
Term endedJuly 18, 2023
Patent numberCA 2493499 C
Classification (IPC)C12N15/11 +2 more

Timeline

Timeline From CIPO dates

2004200620082010201220142016201820202022Application filedJuly 18, 2003Patent grantedApril 12, 2016Term endedJuly 18, 2023

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.