Process for the preparation of phenylalanine enamide derivatives
CA 2492441 A1 · Owner: Celltech R & D Limited · Inventors: Skead, Benjamin Mark; Brookes, Michael Handforth; Tyrrell, Nicholas David
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A process for the preparation of a class of phenylalanine enamide derivatives is described formula (1) wherein: Ar1 is an optionally substituted aromatic or heteroaromatic group; L2 is a linker group selected from -N(R4)- where R4 is a hydrogen atom or an optionally substituted straight or branched C1-6alkyl group, -CON(R4)-, or -S(O)2N(R4)-; R1 is a carboxylic acid (-CO2H) or a derivative or biostere thereof; R2 is a hydrogen atom or a C1-6alkyl group; Rx, Ry and Rz which may be the same or different is each an atom or group - L1(Alk1)n(R3)v; and the salts, solvates hydrates and N-oxides thereof; which , comprises reacting a compound of formula (2): wherein: Qa is a group -N(R4)H; …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 16, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended July 16, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 16, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.