Detecting receptor oligomerization
CA 2490654 C · Owner: Chan-Hui, Po-Ying · Inventors: Pidaparthi, Sailaja; Singh, Sharat; Dua, Rajiv
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Methods are provided for detecting formation of oligomeric complexes of molecules on the surface of cell membranes. These methods employ pairs of tagged probes and cleaving probes, each of which binds specificly to a cell surface molecule. The tagged probe includes a molecular tag that is linked to a first binding compound through a cleavable linkage and the cleaving probe , includes a second binding agent and a cleavage-inducing moiety that can cleave the linkage when within a defined proximity thereto. Binding of the two probes to cell surface molecules that have formed an oligomeric complex results in release of the molecular tag from the binding compound providing a measure of , …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed July 17, 2003 and granted February 7, 2012. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended July 17, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by July 17, 2025.
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Timeline
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Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.