Arylsulfonylhydroxamic acid and amide derivatives and their use as protease inhibitors
CA 2490646 A1 · Owner: Mcdonald, Joseph J. · Inventors: Mischke, Deborah A.; Kolodziej, Steve A.; Rico, Joseph G.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
This invention is directed generally to hydroxamic acid and amide compounds (including salts of such compounds), and more particularly, to aryl- and , heteroaryl-~arylsulfonylmethyl hydroxamic acids and amides that inter alia, inhibit protease activity, particularly matrix metalloproteinase (also known as "matrix metalloprotease" or "MMP") activity and/or aggrecanase activity. These compounds generally correspond in structure to formula (I): wherein Al A2, A3, El, E2, E3, and E4 are as defined in this patent. This invention also is directed to compositions of such compounds intermediates for the syntheses , of such compounds methods for making such compounds, and methods for treating …
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 25, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 25, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 25, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.