Tryptophan as a functional replacement for adp-ribose-arginine in recombinant proteins
CA 2490290 A1 · Owner: Bortell, Rita · Inventors: Stevens, Linda; Bortell, Rita; Bourgeois, Christelle
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
A method is disclosed for producing a polypeptide with a modified activity or stability, by replacing an arginine residue capable of being ADP-ribosylated with a tryptophan or a phenylalanine. In one embodiment compositions are , provided that include polypeptides such as alpha defensin, with arginine-totryptophan or arginine-to-phenylalanine substitutions where the arginine , residue is capable of being ADP-ribosylated. In another embodiment methods , are disclosed for modifying an immune response in a subject.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed June 27, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended June 27, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by June 27, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.