Improved receptor detection
CA 2487513 A1 · Owner: Singh, Rajendra · Inventors: Singh, Rajendra; Rouhani, Riaz; Naqvi, Tabassum
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Improved results are obtained using in an enzyme fragment complementation assay, as an enzyme donor a fragment of .beta.-galactosidase of from 36 to 50 amino acids joined to a ligand capable of binding to a receptor other than an immunoglobulin or fragment thereof. Conveniently for enzyme assays, enzyme , binding site inhibitors are conjugated to the enzyme donor whereby binding of , the enzyme to the binding site inhibitor results in a reduction in the turnover rate of .beta.-galactosidase in the presence of EA and a substrate capable of producing a detectable signal. Analogously ligands for membrane , receptors may be conjugated to the ED for measurement of membrane receptors.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 29, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 29, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 29, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.