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Methods and compositions for regulation and manipulation of steroidogenesis

CA 2486408 A1 · Owner: Bose, Himangshu S · Inventors: Miller, Walter L; Bose, Himangshu S; Lingappa, Vishwanath R

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Abstract From the Canadian patent

The steroidogenic acute regulatory protein (StAR) a mitochondrial protein , required for stress responses reproduction, and sexual differentiation of male fetuses is shown to exert its activity transiently at the outer mitochondrial membrane (OMM) rather than in its final resting place in the matrix, and that its OMM residency time and activity are regulated by its speed of mitochondrial import. This may be the first example of a mitochondrial protein exerting its biological activity in a compartment other than that to which it is finally targeted. This unique system which permits steroidogenic cells to initiate and terminate massive levels of steroidogenesis within a few minutes, …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed May 20, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 20, 2023.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 20, 2025.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledMay 20, 2003
GrantedNo grant recorded
Term endedMay 20, 2023
Patent numberCA 2486408 A1
Classification (IPC)C07H21/02 +2 more

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2004200620082010201220142016201820202022Application filedMay 20, 2003Term endedMay 20, 2023

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.