Generation and selection of protein library in silico
CA 2485732 A1 · Owner: Luo, Peizhi · Inventors: Cao, Yicheng; Hsieh, Mark; Zhong, Pingyu
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides a methodology for efficiently generating and screening protein libraries for optimized proteins with desirable biological functions, such as improved binding affinity towards biologically and/or therapeutically important target molecules. The process is carried out computationally in a high throughput manner by mining the ever-expanding databases of protein sequences of all organisms especially human. In one , embodiment, a method for constructing a library of designed proteins comprising the steps of: providing an amino acid sequence derived from a lead protein, the amino acid sequence being designated as a lead sequence; comparing the lead sequence …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed May 20, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended May 20, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by May 20, 2025.
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Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.