Oral dosage forms comprising fenofibrate

Abstract From the Canadian patent

Disclosed is a pharmaceutically acceptable oral dosage form comprising fenofibrate, phospholipid, a buffer salt a water-soluble bulking agent , selected from maltodextrin mannitol, and combinations thereof, a cellulosic additive, beads or crystals of a pharmaceutically acceptable water-soluble excipient support material, a polyvinylpyrrolidone or crospovidone croscarmellose sodium, granular mannitol sodium dodecyl sulfate, silicon , dioxide and a stearate, wherein the fenofibrate is in the form of microparticles, and wherein at least a portion of the phospholipid is coated on the surfaces of the fenofibrate microparticles the phospholipid coated , microparticles are embedded in a …