A dna enzyme to inhibit plasminogen activator inhibitor-1
CA 2483007 C · Owner: The Trustees Of Columbia University In The City Of New York · Inventors: Itescu, Silviu
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The present invention provides DNAzymes and ribozymes that specifically cleave PAI-1-encoding mRNA. The present invention also provides antisense oligonucleotides that specifically inhibit translation of PAI-1-encoding mRNA. The invention also provides various methods of inhibiting the expression of PAI-1, and methods of treating diseases by such. Finally the invention provides pharmaceutical compositions containing the instant DNAzymes ribozymes, antisense oligonucleotides, or other inhibitors of PAI-1 expression as active ingredients.
Read the whole patent
Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed April 23, 2003 and granted May 22, 2018. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended April 23, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by April 23, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.