Hbv drug resistance detection methods
CA 2480382 C · Owner: Innogenetics N.V. · Inventors: Bozdayi, Abdurrahman Mithat
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
New polymorphisms in the nucleic acid sequences of the DNA polymerase/reverse transcriptase open reading frame and viral surface antigen open reading frame of the hepatitis B virus are reported. In particular the present invention , relates to the mutation YMDD .fwdarw. YSDD in the HBV reverse transcriptase domain and to the W196V mutation in the small HBV viral surface antigen. Said polymorphisms are affecting the detection of drug resistance mutations by genotypic methods and diagnostic kits based thereon. The present invention relates to methods and diagnostic kits for detection of a HBV virus comprising said nucleic acid polymorphisms. In particular those methods utilizing , …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed March 29, 2002 and granted December 22, 2015. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended March 29, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 29, 2024.
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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.