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Crystalline forms of quetiapine hemifumarate

CA 2479668 A1 · Owner: Lifshitz-Liron, Revital · Inventors: Dolitzky, Ben-Zion; Lidor-Hadas, Rami; Kovalevski-Ishai, Eti

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Abstract From the Canadian patent

The present invention relates to novel crystalline forms of quetiapine hemifumarate (I), denominated quetiapine hemifuramate form II and quetiapine hemifuramate form III. These novel crystalline forms of quetiapine hemifuramate have been characterized by methods including x-ray powder diffraction (XRD), Fourier transform IR spectroscopy (FTIR) differential , scanning calorimetry (DSC) and thermal gravimetric analysis (TGA). Methods for preparation of the novel crystalline quetiapine hemifuramate form II as its chloroform solvate and its dichloromethane solvate form III as its , chloroform solvate, and form I are provided.

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed March 20, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended March 20, 2023.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by March 20, 2025.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledMarch 20, 2003
GrantedNo grant recorded
Term endedMarch 20, 2023
Patent numberCA 2479668 A1
Classification (IPC)C07D417/04 +1 more

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2004200620082010201220142016201820202022Application filedMarch 20, 2003Term endedMarch 20, 2023

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.