Ricin vaccine and methods of making and using thereof
CA 2477094 A1 · Owner: Millard, Charles B. · Inventors: Olson, Mark A.; Wannemacher, Robert W.; Millard, Charles B.
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Disclosed herein are polypeptides and variants thereof comprising a polypeptide sequence having substantial identity to ricin A chain (RTA0 that lack detectable N-glycosidase-rRNA activity or exhibit reduced N-glycosidaserRNA activity as compared to controls and methods of making and using thereof. The polypeptides and variants have a greater solubility in aqueous solutions of physiological pH and ionic strength than RTA and also retain the integretiy of the neutralizing immunological epitope of wild type RTA. Also disclosed are immunogenic compositions that may be used to immunize a subject against ricin intoxication. Methods of immunizing against treating, and preventing ricin , …
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 27, 2002. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 27, 2022.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 27, 2024.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
Timeline From CIPO dates
Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.