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Methods of producing phosphitylated compounds

CA 2477039 A1 · Owner: Reddy, Kalakota · Inventors: Werner, Christian; Nerenz, Franc; Reddy, Kalakota

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Abstract From the Canadian patent

Provided are methods of producing phosphitylated compounds including 3'-, O~phosphoramidites, comprising the step of reacting a hydroxyl-containing compound with a phosphitylating agent in the presence of a phosphitylation activator selected from the group consisting of (1) acid-base complexes derived from an amine base of Formula (I) wherein R R1, and R2 are , independently C1-C10 alkyl C1-C10 cycloalkyl, C1-Cl0 aryl, Cl-C10 aralkyl Cl-, C10 heteroalkyl, or Cl-CIO heteroaryl; (2) acid-base complexes derived from an amine base of Formula (II) wherein R3, R4 R5, R6, and are independently , hydrogen C1-C10 alkyl, Cl-C10 cycloalkyl, Cl-C10 aryl Cl-CIO aralkyl, Cl-CIO , heteroalkyl, or …

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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.

Why it's free to use

  • Filed February 24, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 24, 2023.
  • A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 24, 2025.
  • We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
FiledFebruary 24, 2003
GrantedNo grant recorded
Term endedFebruary 24, 2023
Patent numberCA 2477039 A1
Classification (IPC)C07B47/00 +2 more

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2004200620082010201220142016201820202022Application filedFeb 24, 2003Term endedFeb 24, 2023

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Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.