A method for generating engineered cells for locus specific gene regulation and analysis
CA 2473741 C · Owner: Grasso, Luigi · Inventors: Sass, Philip M.; Nicolaides, Nicholas C.; Grasso, Luigi
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
Inhibitors of mismatch repair can be used to generate hypermutable cells and organisms. By inhibiting this process in cells new cell lines and varieties , with novel and useful properties can be prepared more efficiently than by relying on the natural rate of homologous recombination. These methods are useful for generating targeted loci that can alter the expression profiles of target genes as well as tag exons of gene with a reporter marker to facilitate the monitoring of a given gene product when the host is grown under different conditions or exposed to biological and chemical entities.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed January 17, 2003 and granted December 22, 2015. A Canadian patent filed from October 1, 1989 lasts 20 years from filing, so its term ended January 17, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by January 17, 2025.
- We check Canadian rights only. A patent in its family in another country could still be in force: check its family on Google Patents.
Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.