Formulation strategies in stabilizing peptides in organic solvents and in dried states
CA 2472956 A1 · Owner: Martin-Moe, Sheryl · Inventors: Wang, Wei; Martin-Moe, Sheryl; Wang, Yu-Chang John
Overview
Its claims, description and drawings are in the Canadian Patents Database.
Open the CIPO recordAbstract From the Canadian patent
The invention relates to stabilized formulations of therapeutically active peptides, particularly PACAP 66. Formulations of the invention include a peptide containing at least one histidine residue a transition metal salt and , an organic solvent. The above formulations may contain peptides that have at least one asparagine residue and are acidified and dried (such as spray-dried or freeze-dried) before formulation preparation. Other formulations of the invention relate to stabilized formulations of PACAP 66 or peptides containing an asparagine residue, which are acidified and dried (such as spray-dried or freeze-dried) with or without a transition metal salt.
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Listed from its CIPO record in Patent Yard's archive of Canadian patents past their term. Its claims, description and drawings are in the CIPO record and on Google Patents, and the Claude kit works from them.
Why it's free to use
- Filed February 14, 2003. No grant is recorded for it in Canada; had it been granted, its 20-year term would have ended February 14, 2023.
- A certificate of supplementary protection adds at most two years for a drug, so even that would have ended by February 14, 2025.
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Timeline
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Sources & verification
Official CIPO records
Everything on this page comes from the CIPO record linked above. Contains information licensed under the Open Government Licence – Canada.